Technical Details of Methyl (S)-hexahydropyridazine-3-carboxylate hydrochloride CAS No.380223-17-6

CAS No	380223-17-6
Molecular Weight	180.63
Molecular Structure	C6H13ClN2O2

Specifications of Methyl (S)-hexahydropyridazine-3-carboxylate hydrochloride CAS No.380223-17-6

Purity / Strength	97%

* Notes :
MDL No.: MFCD33019683
Storage: Inert atmosphere, 2-8°C

Applications of Methyl (S)-hexahydropyridazine-3-carboxylate hydrochloride CAS No.380223-17-6

Synthesis of RMC-6236 (RAS-ON Multi-Inhibitor)
This intermediate is notably linked to the synthesis of RMC-6236, a breakthrough drug currently in clinical trials. It forms part of the core structure that allows the drug to bind to the active, GTP-bound state of KRAS. Increases the drug's potency & improves selectivity.

Features / Description of Methyl (S)-hexahydropyridazine-3-carboxylate hydrochloride CAS No.380223-17-6

Methyl (S)-hexahydropyridazine-3-carboxylate hydrochloride is a saturated six-membered ring containing two nitrogen atoms (a hexahydropyridazine) with a methyl ester and a carboxylic acid derivative. This intermediate ensures the final drug molecule has the exact spatial orientation needed to dock into those pockets.Typically supplied as a hydrochloride (HCl) salt to improve its stability and solubility during the chemical manufacturing process.